A Microfluidic Device for Single Cell-Liposome Fusion

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Microfluidic device for single-cell analysis.

We have developed a novel microfluidic device constructed from poly(dimethylsiloxane) using multilayer soft lithography technology for the analysis of single cells. The microfluidic network enables the passive and gentle separation of a single cell from the bulk cell suspension, and integrated valves and pumps enable the precise delivery of nanoliter volumes of reagents to that cell. Various ap...

متن کامل

ERRATUM: Integrated microfluidic device for single-cell trapping and spectroscopy

Optofluidic microsystems are key components towards lab-on-a-chip devices for manipulation and analysis of biological specimens. In particular, the integration of optical tweezers (OT) in these devices allows stable sample trapping, while making available mechanical, chemical and spectroscopic analyses.

متن کامل

Microfluidic Device for Single Cell Studies of Spinal Cord Injury

Spinal Cord Injury is damage to the spinal cord due to physical trauma. Study of spinal cord injury has hardly been achieved at the single cell level. Polymer microfluidics devices may provide a unique in vitro platform for studying single neuronal responses to mechanical forces. For example, one device developed in our lab, called microchannel device, is made from poly (dimethylsiloxane) (PDMS...

متن کامل

A microfluidic electroporation device for cell lysis.

We demonstrate a micro-electroporation device for cell lysis prior to subcellular analysis. Simple circuit models show that electrical lysis method is advantageous because it is selective towards plasma membrane while leaving organelle membrane undamaged. In addition, miniaturization of this concept leads to negligible heat generation and bubble formation. The designed microdevices were fabrica...

متن کامل

Microfluidic Chips for Liposome Production

In recent years, the development of nanoand micro-particles has attracted considerable 11 interest from researchers and enterprises, because of the potential utility of such particles as drug 12 delivery vehicles. Amongst the different techniques employed for the production of nanoparticles, 13 microfluidic-based methods have proven to be the most effective for controlling particle size and 14 ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biophysical Journal

سال: 2012

ISSN: 0006-3495

DOI: 10.1016/j.bpj.2011.11.3298